OneSkin OS-01 Face Topical Supplement

OneSkin OS-01 Face Moisturizer — Topical Supplement

OneSkin's OS-01 Face Moisturizer is a science-backed daily face and neck cream powered by the proprietary OS-01 Peptide™ (Decapeptide-52) — the only peptide scientifically proven to reverse skin aging at the cellular level by targeting senescent cells. This 50ml topical supplement is designed to reduce the most visible signs of aging while supporting long-term skin health.

What makes this product unique

At the heart of the formula is the OS-01 Senescence Blocking Peptide™, which blocks the activity of collagen-degrading cells and stimulates skin regeneration from within. The result is firmer, smoother, and more radiant skin — confirmed by peer-reviewed clinical study results.

Key clinical results (double-blind, placebo-controlled study):

• 100% of participants reported improved skin smoothness
• 96% showed improvement in firmness, radiance, and evenness of skin tone
• 90% observed improved elasticity
• 86% reported a reduction in the appearance of fine lines and wrinkles
• 87% reduction in fine lines and wrinkles (data from image analysis)
• 23% average increase in epidermal thickness

Key active ingredients

• Decapeptide-52 / OS-01 Peptide™ — Proprietary senolytic peptide that reverses skin aging at the cellular level
• Hyaluronic Acid (three molecular weights: Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer) — Stimulates collagen and elastin production, supports epidermal regeneration, and maintains hydration in every layer of the skin
• Niacinamide — Vitamin B3 that improves skin texture by stimulating protein synthesis in the epidermal layer
• Pentaclethra Macroloba (Pracaxi) Oil — Rich moisturizing oil with anti-inflammatory, antioxidant, antibacterial, and antifungal properties
• Carapa Guianensis Seed (Andiroba) Oil — Seed oil that supports healthy collagen production and minimizes inflammation
• Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato) — Extract from an Amazonian tree that smoothes wrinkles, reduces skin stress, and promotes healing
• Allantoin — Skin-conditioning ingredient that moisturizes and soothes irritation

Formula properties

The formula is 100% free of: fragrances, parabens, sulfates, lanolin, MCI/MI, DEA, heavy metals, talc, petrolatum/paraffin/mineral oils, gluten, and phthalates. It is non-comedogenic and dermatologically tested — safe for sensitive skin, including skin with eczema.

The packaging features a reusable case with a refillable insert, significantly reducing the product's environmental footprint. The product is Leaping Bunny certified and accepted by the National Eczema Association.

Benefits at a glance

• Intensely moisturizes and strengthens the skin's protective barrier
• Firms and smooths the skin of the face and neck
• Evens skin tone, improves texture, and adds radiance
• Supports collagen production at the cellular level
• Suitable for sensitive skin; fragrance-free

Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose Hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate

Each ingredient is carefully selected to ensure our products are effective, safe, and suitable for various skin types.

Once we receive your return, we will issue a refund within 5-7 business days. The funds will be returned to the same payment method
you selected when placing your order. More information on how to initiate a return can be found on the Returns page - you can also contact our customer service, we'll be happy to help. Shop with peace of mind, you're in good hands.