# Medicube Zero One Day Exosome Shot 25,000 Serum
Inspired by the principles of micro-needling, **Medicube Zero One Day Exosome Shot 25,000** is a microscopic, needle-shaped booster designed to address a wide spectrum of skin concerns—from enlarged pores and uneven texture to dullness and a weakened skin barrier. Enriched with **15 million patented exosome shots**, the formula physically delivers active ingredients deep into the pores, enabling intensive daily care from the comfort of your home.
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## What makes it unique
The INTENSE (25000) variant contains the highest concentration of **Lactobacillus Extracellular Vesicles (154 ppm)** and **Milk Exosomes (10 ppm)**, supplemented with exosome-coated spicules (Hydrolyzed Sponge) that create micro-channels in the skin, increasing cosmetic absorption by up to **+242%** compared to standalone use.
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## Clinically proven results
- **Pore tightening:** –21.1%
- **Pore visibility:** –21.1%
- **Pore surface improvement:** –15.3%
- **Pore volume improvement:** –16.7%
- **Dead skin cell reduction:** +88.7%
- **Radiance improvement:** +51.7%
- **Skin barrier strengthening:** +54.2%
- **Surface hydration improvement:** +7.6%
- **Sebum reduction:** +8.9%
- **Texture evening:** +4.1%
*Results are from the Medicube Exosome Shot research report and survey. Effects may vary depending on the individual. Studies conducted by the Global Institute of Dermatological Science (August–September 2022).*
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## Key benefits
- **Non-comedogenic** — does not clog pores
- **Low irritation tested** — suitable for sensitive skin after patch testing
- **Gluten-free** — no artificial colorants
- Formula free from parabens, sulfates, fragrances, mineral oils, silicones, retinol, phenoxyethanol, and over 50 other potentially harmful ingredients
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## Key ingredients (INTENSE 25000 formula)
- **Lactobacillus Extracellular Vesicles (154 ppm)** — delivering active ingredients via exosomes, deep skin renewal
- **Milk Exosomes (10 ppm)** — cell communication, skin regeneration
- **Hydrolyzed Sponge (spicules)** — micro-needling action opening pathways for active ingredient absorption
- **Niacinamide** — brightens skin, minimizes pores, controls sebum
- **Panthenol** — soothes and strengthens the skin barrier
- **Gluconolactone** — gentle PHA exfoliation for refined texture
- **Betaine Salicylate** — BHA-type ingredient for pore cleansing and blackhead reduction
- **Ceramide NP** — rebuilds and strengthens the skin's lipid barrier
- **Palmitoyl Pentapeptide-4 and Palmitoyl Tripeptide-5** — peptide complex supporting firming and anti-aging benefits
- **Adenosine** — soothes skin and supports elasticity
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## How to use
**For beginners:**
1. After cleansing, prepare your skin with Medicube Zero Pore Pads or another hydrating toner.
2. Apply Zero One Day Exosome Shot to the selected area (e.g., areas with uneven texture, enlarged pores) and gently pat until absorbed.
3. Finish your routine with Medicube Collagen Jelly Cream or your daily water-based moisturizer.
**Standard use:**
1. After cleansing, apply Zero One Day Exosome Shot to your entire face, avoiding the eye and mouth areas. For best results, use as the first step in your skincare routine.
2. Gently massage and pat the product to allow the needle-shaped formula to absorb deeply into the skin.
3. Finish with Medicube Collagen Jelly Cream or your daily water-based moisturizer.
**Pro tip:** To maximize effects, apply Zero One Day Exosome Serum after using the "Air Shot Mode" of the AGE-R Booster Pro device.
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*Volume: 13 ml*
