Dong-A Pharm Melatoning Cream – Targeted Action on Hyperpigmentation
Dong-A Pharmaceutical’s Melatoning Cream is a clinically developed, over-the-counter (OTC) whitening cream designed to reduce unwanted skin discoloration. With Hydroquinone (USP) 2% as an active ingredient, it gradually and effectively lightens darkened areas of the skin caused by excessive melanin production.
Indications for Use
The cream is intended for the gradual lightening of hyperpigmented areas of the skin, including:
• Melasma (liver spots / chloasma)
• Freckles
• Age spots
• Other areas with excessive melanin pigmentation
Active Ingredient
• Hydroquinone (USP) 20 mg per gram (2%) — a recognized depigmenting dermatological agent that works by inhibiting the enzymatic oxidation of tyrosine and suppressing the metabolic processes of melanocytes, thereby limiting melanin overproduction in target areas.
Appearance and Format
The cream is a milky white cream in a practical tube packaging, available in sizes:
• 30 g / tube
• 50 g / tube
Why Hydroquinone 2%?
Hydroquinone has been used in dermatology for decades as the gold standard among topical depigmenting agents. At a 2% concentration, it is widely recognized as a safe and effective OTC substance for treating localized hyperpigmentation. It works gradually with regular daily use, making it suitable for localized reduction of freckles, melasma, and age spots.
Key Usage Tips
• Apply 1–2 times daily (morning and/or before bed) only to affected skin areas.
• Before the first full application, perform a 24-hour patch test (e.g., behind the ear or on the inner arm) — continue regular use only if no reaction occurs.
• Apply using a spot method directly to the hyperpigmented area — avoid applying to surrounding, unaffected skin.
• If used during the day, reapply sunscreen every 2–3 hours when outdoors, as UV exposure can weaken the lightening effect. It is recommended to use the product primarily in the evening, before bed.
About Dong-A Pharmaceutical
Dong-A Pharmaceutical is a leading South Korean pharmaceutical company with a rich tradition in dermatology and consumer health. The Melatoning line reflects their commitment to creating science-based skincare solutions that meet stringent OTC regulatory standards.